Platelet Society Summer Studentships – Eloise
Eloise Marriott
University of Birmingham
(Supervisor Dr Caroline Kardeby and Dr John-Peter Ganda Mall)
Tell us about yourself:
My name is Eloise and I’m from Oxfordshire; I am currently entering my third year studying biomedical science at the University of Birmingham. In my spare time, I like to crochet, rock climb, and do pole fitness.
How did you hear about the Platelet Society Summer Studentship Scheme, and why did you want to get involved?
I heard about the scheme through an advertisement that was emailed to biomedical students. Parkinson’s Disease (PD) and other neurodegenerative diseases are of great interest to me, and this is why I wanted to get involved. I had not heard about the association between PD and thromboembolism/stroke before, so I was eager to find out more. I was also keen to gain some experience in the lab as early as possible to aid me with my third-year project, potential PhD, and future careers.
What was the focus of your project?
My project involved looking at α-synuclein – the pathogenic protein in PD – and heparin – released when mast cells degranulate – and their effect on platelet activation in healthy volunteers. We used multiple assays to measure platelet activation – which allowed me to practice multiple experimental methods.
Did you have any expectations before you started?
I expected there to be a lot of new things that I had to process, remember and get used to. I thought that it would be a challenge, but I assumed I would be well supported so I could slowly increase my level of responsibility.
How did the project go? Did you enjoy your research time?
I really enjoyed the project; I liked the responsibility (once I knew what I was doing) and I was really invested in the science. The lab environment was friendly and supportive, and I liked that my days were structured. The results were novel and unpredictable which means we tried a lot of different types of experiments – which kept things very engaging and ensured each week was varied.
What have you learnt about yourself and the research environment?
This project has been an incredibly valuable learning experience for me. Not only has it helped me understand how and why different methods should be used and how to apply controls. Due to constant circumstantial changes in the lab, I was able to improve my problem-solving and adaptability. This project has allowed me to practice and learn dilution calculations, data handling and statistical analysis. It also helped me develop my personal skills – for example how to plan effectively to prevent mistakes and how to best organise my time in a lab. I also learned the valuable lesson of writing things down, focusing on what I’m doing, and how unpredictable science can be.
What advice would you give to someone considering applying next time?
My advice would be to make sure that you have an interest in the area you’re applying for. It allows you to naturally put more time and effort into the background reading and whilst you’re in the lab to gain more understanding and have the most enriching time possible. It will also mean you’ll be more invested in the project/results and will get more enjoyment out of the experience.