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University of Bristol

Targeted Protein Degradation as a Cutting-Edge Tool to Study Tyrosine Kinases in Platelet Signaling and Function

👉 PhD project opportunity!

🎯 Ever wondered how we can control protein expression inside anucleate cells to study complex signaling networks?

Exciting 4-year PhD studentship available as part of the SWBio DTP PhD programme at the University of Bristol, using 🎯 Proteolysis-Targeting Chimeras (PROTACs) and molecular modeling to explore how tyrosine kinases regulate platelet signaling and function.

You will gain hands-on experience in targeted protein degradation, computational modeling, and platelet biology, and will be jointly supervised by me, Dr Robin Corey and Prof Varinder Aggarwal in a vibrant interdisciplinary training environment.

Supervisory team
Main supervisor: Prof Ingeborg Hers (University of Bristol)
Second supervisor: Dr Robin Corey (University of Bristol)
Other supervisors: Prof Varinder Aggarwall (University of Bristol)

Further details on the project – swbio-26-project-61

👉 Apply by the 3rd December 2025. Check out further details at the DTP website

To apply for this job please visit www.swbio.ac.uk.